Business and News Update November 2011

People

• Pharmaceutical service provider Diapharm (Münster, Germany) has expanded its Regulatory Affairs team with the addition of Petra Kist and Stefanie Zumdick, PhD.

• Quintiles (Durham, NC) has made several additions to its team including Troy Norris as Vice President and Managing Director for the Product Development and Commercialization practice of Quintiles Consulting, and Jeffrey A. Spaeder, MD, as its Chief Medical and Scientific Officer. Spaeder succeeds Oren Cohen, MD, who now leads the company's Phase I clinical research business.

• ACR Image Metrix (Philadelphia, PA) has hired Kathy Freeman as the Business Development Manager for the East Coast.

• ICON (Dublin, Ireland) announced the appointment of Mario Rocci, PhD, to the position of President, ICON Development Solutions.

• Premier Research Group (Philadelphia, PA) has hired Mark P. Sneff to the position of Vice President, Human Resources. In this role, Sneff will be responsible for the global human resources function and staff in support of the company's strategic goals.

• Southern Research Institute (Birmingham, AL) announced that pharmaceutical executive Mark J. Suto, PhD, has been named Vice President of the Drug Discovery Division.

• TKL Research (Rochelle Park, NJ) announced that Kevin Vernarec has assumed the newly created position of Vice President of Operational Excellence.

• Steve Swanson has been appointed Chief Executive Officer of DAC Patient Recruitment Services (Dallas, TX).

• Tomasz H. Zastawny has been appointed MTZ-US Clinical Research's (Warsaw, Poland) Chief Executive Officer where he will expand and oversee the entire North American operation.

• PharmaNet Development Group (Princeton, NJ) has appointed George Scott, PhD, as Vice President, Bioanalytical Services, where he will provide leadership for PharmaNet's GLP-compliant bioanalytical laboratories in the United States and Canada.

• ACM Global Central Lab (Rochester, NY) has appointed Suzanne Dale, PhD, as the Director of Microbiology, and Sara L. Diaz as Manager of Hematology.

• PRA (Raleigh, NC) has recently appointed Frederick T. Lewis, DO, as Vice President, Psychiatry–Scientific Affairs in its Therapeutic Expertise group.

• Leading the Clinical Trial Management services and supporting the company's business development team to advance Human Abuse Liability research, Matthew Iverson has taken on the role of Vice President at Lifetree Clinical Research (Salt Lake City, UT).

Alliances

• Pearl IRB (Indianapolis, IN) and Trafalgar Ethics Board (Toronto, Canada) have formed a partnership to provide central IRB services.

• Preclinical Oncology Services Limited (PRECOS) (Nottingham, UK) has signed a partnership agreement with Reliable Cancer Therapies (RCT) (Verbier, Switzerland) to provide scientific validation of existing data for cancer therapies. The partnership will see PRECOS provide drug efficacy work to support RCT's research on complementary medicines, so that evidence-based treatment choices can be made by patients and health professionals.

• Clinigene International (Bangalore, India) and Spaulding Clinical Research (West Bend, WI) have formed a strategic partnership agreement that allows both organizations to engage pharmaceutical clients strategically and accelerate first-in-human to proof-of-concept clinical development.

• Esoterix Clinical Trials Services (Cranford, NJ) has formed a strategic alliance with the David H. Murdock Research Institute (Kannapolis, NC) to provide its clients with access to enhanced assay development services.

• ICON (Dublin, Ireland) has been chosen by Bristol-Myers Squibb Company (New York, NY) as a preferred provider for full-service clinical pharmacology and exploratory clinical studies.

• StudyManager (Seattle, WA) announced that Meagan Medical (Vancouver, WA), a clinical research and product development company, has deployed StudyManager Evolve software to manage its latest clinical study.

Awards

• Almac's (Souderton, PA) Clinical Services business unit was presented with the ASQ Philadelphia Section Large Company Member of the Year award at the section's awards dinner held in Malvern, PA. The award is presented annually to a company with more than 200 employees with the leading participation in section activities.

• Novella Clinical's (Research Triangle Park, NC) Executive Vice President Elaine Wingate has been honored by Triangle Business Journal through its Women in Business Awards program.

• Inc. Magazine has recognized MedNet Solutions (Minnetonka, MN) as one of the fastest-growing privately held companies in the United States by including the company on its "Inc. 5000" list for the fifth straight year.

From left are Cathy Robinson, Tania Davis, Christine Gallagher, Susan Beattie, Jill Cooper, and Maire Mullin. Almac is carrying out genetic research to make advances in the field of personalized medicine.

Company News

• Almac (Craigavon, UK)switched up their usual workwear for jeans in honor of Jeans for Genes Day. By making a donation to the national charity, Jeans for Genes, staff helped to fund research into a wide range of genetic disorders which affect around one in 25 children born in the United Kingdom.

• Beaufort (Norfolk, VA) has added quality oversight to its services for clients in the pharmaceutical, diagnostic, and medical device industries.

• Gen-Probe's Tepnel Pharma Services (Manchester, UK) announced that its analytical laboratories in Livingston, Scotland, have successfully passed a GMP inspection by the US Food and Drug Administration without any "Form 483" citations.

• Biomedical Research Alliance of New York (Lake Success, NY) research sites now have the opportunity to improve their patient stipend payments and manage their study budgets with a discount from Greenphire's ClinCard System. The ClinCard System enables sites and sponsors to deliver subject payments in a controlled and automated manner in compliance with industry regulation and in accordance with the specific requirements of each study.

• MTZ Clinical Research (Warsaw, Poland), an early clinical development services provider, announced the formation of MTZ-US Clinical Research in Massachusetts. This new office location in the Boston area will allow MTZ to better meet the needs of its customers throughout biotechnology hubs in the United States.

• PRA (Raleigh, NC) has announced the release of the third edition of respiratory care expert Jack Wanger's book, Pulmonary Function Testing: A Practical Approach, recently published by Jones & Bartlett Learning in Sudbury, MA.

• Marken (Miami, FL) launched their Latin America regional depot network with facilities in Mexico City and Buenos Aires.

• Covance (Princeton, NJ) has expanded its drug metabolism services to include drug-transporter interactions with eight human transporters. Under this expansion, Covance now offers assessment of drug-transporter interactions involving major human transporters, key to drug disposition in a stably transfected, cell-based format.

• Clinilabs (New York, NY) has been selected to conduct a Phase I clinical trial of an investigational new drug for insomnia. The study will assess the safety, tolerability, pharmacokinetics, and pharmacodynamics in a group of healthy subjects and in otherwise healthy subjects who suffer from primary insomnia.

• CRF Health (Plymouth Meeting, PA) announced an open ePRO integration interface, which enables sponsors and CROs to integrate their own eClinical systems with CRF Health's ePRO platform, TrialMax®, to provide data collected from patients in real time to all study stakeholders.

• Catalent Pharma Solutions (Somerset, NJ) and Aptuit (Greenwich, CT) announced an agreement for Catalent to acquire the Clinical Trial Supplies business of Aptuit LLC for cash consideration of $410 million on a cash and debt free basis.

New Facilities

• Chiltern International Limited (London, UK) has established a new legal entity in Israel.

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Comprehensive Clinical Development

has expanded with the relocation of its corporate headquarters to Miramar, FL.