Applied Clinical Trials
The financial aspect of standard of care in patient treatment has become a major issue for many companies conducting clinical research. Many industry monitors, self-appointed and otherwise, have highlighted the issue of payments to physicians by pharmaceutical companies, including the fair market payment of clinical grants, as possibly influencing physician behavior. Subjects in later phase clinical research must have the malady being treated in the clinical trial. Consequently, many of the treatments these patients receive would and should be covered by third-party payers, typically government agencies or commercial insurance companies.
The financial aspect of standard of care in patient treatment has become a major issue for many companies conducting clinical research. Many industry monitors, self-appointed and otherwise, have highlighted the issue of payments to physicians by pharmaceutical companies, including the fair market payment of clinical grants, as possibly influencing physician behavior. Subjects in later phase clinical research must have the malady being treated in the clinical trial. Consequently, many of the treatments these patients receive would and should be covered by third-party payers, typically government agencies or commercial insurance companies.
Double Dip: Third-Party and Pharma
In addition to questions of fair market value, senior clinical development management is simply looking for better ways to deal with rapidly increasing drug development costs. One way is to avoid double payments for medical procedures that are covered by third-party payers. A review of over 100 current protocols1 demonstrates that, while companies are introducing standard of care considerations into their clinical grants, a substantial amount of potential payment overlap still exists. An additional 22% of clinical grants, beyond what pharmaceutical companies already consider as standard of care, is usually covered by these third-party payers. Standard of care is no longer a subjective measure, but rather what physicians are paid to treat a patient for a specific indication according to actual payment records.2 Moreover, a large percentage, 80%, of this payment overlap takes place for less expensive procedures, that is, procedures costing less than $1000,—TTC (for more information, please contact help@ttc-llc.com).
1. Subscribers to GrantPlan conduct over 76% of all clinical trials http://ClinicalTrials.gov; March 1, 2010.
2. Trialytics payments data covering over 800 million payment records from commercial insurance companies, Medicare and Medicaid.
Reaching Diverse Patient Populations With Personalized Treatment Methods
January 20th 2025Daejin Abidoye, head of solid tumors, oncology development, AbbVie, discusses a number of topics around diversity in clinical research including industry’s greatest challenges in reaching diverse patient populations, personalized treatment methods, recruitment strategies, and more.
Optimizing Phase III Oncology Trial Recruitment with Data-Driven Insights
February 3rd 2025A pharmaceutical company aimed to launch a Phase III clinical trial for a new oncology drug, focusing on efficient and effective patient recruitment across diverse regions. They evaluated patient populations by analyzing demographics, social determinants of health, and geography. Investigator profiling included practice details, affiliations, referral networks, and clinical trial experience. The final step involved selecting and extracting target lists for implementation.