In-Licensing On the Rise in Europe
Findings show big pharma increasingly turning to other companies for molecules to stock its pipeline.
One snippet that catches the eye in the voluminous documentation accompanying the ruling on competition in the EU pharmaceutical industry includes the finding that “large pharmaceutical companies are increasingly in-licensing new products. Currently 25% of the molecules in clinical development have been acquired from other companies, including smaller firms. This is confirmed by the findings of the sector inquiry and shows the importance of smaller firms for maintaining the innovative character of the pharmaceutical sector.”
Elsewhere, “Companies report that the success rates for biopharmaceutical-based medicines are twice as high as those of chemical molecules in preclinical and clinical development.” In addition, between 2000 and 2007 the originator companies covered by the inquiry spent on average 17% of their turnover generated at global level with prescription medicines on R&D for new or improved prescription medicines, it says. More specifically, “in 2007 approximately 1.5% of global turnover was spent on preclinical research—research to identify potential new medicines, the remaining part mostly on clinical trials and tests.”
At the very least, there should no longer be any EU official who can in the future claim ignorance of the pharmaceutical industry—or of the crucial role played by clinical trials.
Behind the Buzz: Why Clinical Research Leaders Flock to SCOPE Summit
February 7th 2025In this episode, we meet with Micah Lieberman, Executive Conference Director for SCOPE Summit (Summit for Clinical Ops Executives) at Cambridge Innovation Institute. We will dive deep into the critical role of collaboration within the clinical research ecosystem. How do we bring together diverse stakeholders—sponsors, CROs, clinical trial tech innovators, suppliers, patients, sites, advocacy organizations, investors, and non-profits—to share best practices in trial design, program planning, innovation, and clinical operations? We’ll explore why it’s vital for thought leaders to step beyond their own organizations and learn from others, exchanging ideas that drive advancements in clinical research. Additionally, we’ll discuss the pivotal role of scientific conferences like SCOPE Summit in fostering these essential connections and collaborations, helping shape the future of clinical trials. Join us as we uncover how collective wisdom and cross-industry partnerships are transforming the landscape of clinical research.
Reaching Diverse Patient Populations With Personalized Treatment Methods
January 20th 2025Daejin Abidoye, head of solid tumors, oncology development, AbbVie, discusses a number of topics around diversity in clinical research including industry’s greatest challenges in reaching diverse patient populations, personalized treatment methods, recruitment strategies, and more.
Phase III Trial Data Show Subcutaneous Pembrolizumab as Noninferior to IV Keytruda
March 31st 2025Subcutaneous administration of pembrolizumab with chemotherapy demonstrated a nearly 50% reduction in patient chair and treatment room time while maintaining efficacy and safety endpoints compared to intravenous Keytruda.
Phase II ALPACA Trial Shows Lepodisiran Produces Significant, Sustained Lipoprotein(a) Reductions
March 31st 2025Eli Lilly’s lepodisiran, an investigational siRNA therapy, achieved significant and durable reductions in lipoprotein(a) levels, a major genetic risk factor for cardiovascular disease.
