Boehringer Ingelheim and OSE Immunotherapeutics Announce Expansion of Two Solid Tumor Programs
Expanded collaboration seeks to develop first-in-class treatments for cancer and cardio-renal-metabolic diseases.
Boehringer Ingelheim and OSE Immunotherapeutics have announced a major expansion of their already-existing partnership. The duo will be adding two new projects to develop first-in-class treatments—the first focusing on broadening the therapeutic evaluation of an already partnered asset to reach more patients and the second being a new asset acquisition.1
The first project involves anti-SIRPα immuno-oncology compounds BI 765063 and BI 770371, which are being investigated in Phase I clinical studies in advanced solid tumors. In addition to current research, the development of these compounds will now be pursued in cardio-renal-metabolic (CRM) diseases.
The second project is the launch of a new preclinical program, which will develop immune-cell activating treatments based on OSE’s cis-targeting anti-PD1/cytokine platform, acquired by Boehringer Ingelheim.
“We are very pleased to expand our pipeline of potential first-in-class CRM disease therapies, as well as our pipeline of first-in-class T-cell based anti-cancer therapies,” Clive R. Wood, corporate senior vice president and global head of discovery research at Boehringer Ingelheim said in a press release. “The expansion of our partnership with OSE reflects our joint mission to improving patient outcomes in two of the biggest threats to global health.”
“We are excited about adding two highly innovative new development programs to our fruitful collaboration with Boehringer Ingelheim,” Nicolas Poirier, CEO of OSE Immunotherapeutics said in the press release. “We look forward to working with the scientists at Boehringer Ingelheim on the new development programs that have the potential to bring new breakthrough therapy options to patients with CRM diseases and cancer.”
Reference
1. Boehringer Ingelheim and OSE Immunotherapeutics expand collaboration to develop first-in-class treatments for cancer and cardio-renal-metabolic diseases. News release. May 22, 2024. Accessed May 23, 2024. https://www.boehringer-ingelheim.com/science-innovation/human-health-innovation/partnership-first-class-cancer-and-crm-treatments
Behind the Buzz: Why Clinical Research Leaders Flock to SCOPE Summit
February 7th 2025In this episode, we meet with Micah Lieberman, Executive Conference Director for SCOPE Summit (Summit for Clinical Ops Executives) at Cambridge Innovation Institute. We will dive deep into the critical role of collaboration within the clinical research ecosystem. How do we bring together diverse stakeholders—sponsors, CROs, clinical trial tech innovators, suppliers, patients, sites, advocacy organizations, investors, and non-profits—to share best practices in trial design, program planning, innovation, and clinical operations? We’ll explore why it’s vital for thought leaders to step beyond their own organizations and learn from others, exchanging ideas that drive advancements in clinical research. Additionally, we’ll discuss the pivotal role of scientific conferences like SCOPE Summit in fostering these essential connections and collaborations, helping shape the future of clinical trials. Join us as we uncover how collective wisdom and cross-industry partnerships are transforming the landscape of clinical research.
Reaching Diverse Patient Populations With Personalized Treatment Methods
January 20th 2025Daejin Abidoye, head of solid tumors, oncology development, AbbVie, discusses a number of topics around diversity in clinical research including industry’s greatest challenges in reaching diverse patient populations, personalized treatment methods, recruitment strategies, and more.
Phase III Trial Data Show Subcutaneous Pembrolizumab as Noninferior to IV Keytruda
March 31st 2025Subcutaneous administration of pembrolizumab with chemotherapy demonstrated a nearly 50% reduction in patient chair and treatment room time while maintaining efficacy and safety endpoints compared to intravenous Keytruda.
Phase II ALPACA Trial Shows Lepodisiran Produces Significant, Sustained Lipoprotein(a) Reductions
March 31st 2025Eli Lilly’s lepodisiran, an investigational siRNA therapy, achieved significant and durable reductions in lipoprotein(a) levels, a major genetic risk factor for cardiovascular disease.
