Applied Clinical Trials September 2024 Issue (PDF)

Investigators find that most exclusion criteria in critical care randomized clinical trials are justifiable, but 60% include at least one poorly justified exclusion, most commonly affecting pregnant or lactating individuals.

Daejin Abidoye, head of solid tumors, oncology development, AbbVie, discusses a number of topics around diversity in clinical research including industry’s greatest challenges in reaching diverse patient populations, personalized treatment methods, recruitment strategies, and more.

In the study, Calquence plus chemotherapy reduced the risk of disease progression or death by 27%.

The top five episodes of our podcast in the year 2024, highlighted.

In the pivotal trial, patients treated with Omvoh experienced significant improvements in clinical remission and endoscopic response at one year.

An updated long-term analysis of the Phase III KATHERINE trial confirms that adjuvant treatment with Kadcyla (trastuzumab emtansine) significantly improves overall survival and long-term invasive disease–free survival compared to trastuzumab monotherapy in patients with HER2-positive early breast cancer with residual invasive disease.